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Polynucleotides, tired eyes, under eye shadow correction, tear trough filler

3 September 2024

Polynucleotides to Treat Under Eyes

Are You Tired of Looking Tired? Here’s How to Rejuvenate Your Eyes

Do you find yourself constantly battling dark circles and hollows under your eyes? You’re not alone. The delicate skin around the eyes is often one of the first areas to show signs of aging, leaving many searching for effective solutions to rejuvenate their appearance.

What Happens to the Eyes Over Time?

The skin around the eyes is incredibly delicate and thin, making it more vulnerable to environmental and lifestyle factors such as sun exposure, stress, pollution, facial expressions, and the natural aging process. This thin skin also loses collagen and elasticity faster than other areas, and the muscles around the eyes can weaken over time, leading to sagging and thinning.

These changes make the eye area prone to:

  • Dark circles
  • Fine lines, wrinkles, and crow’s feet
  • Puffiness
  • Hollowed areas
  • Sagging eyelids

Unfortunately, these conditions can often make us look older than we feel. Dark circles under the eyes are one of the most common concerns seen in dermatology, and while traditional treatments exist, innovative solutions like polynucleotides are emerging as a promising new approach to rejuvenating the under-eye area.

What Are Polynucleotides?

Polynucleotides are a type of regenerative treatment that stimulates the body’s natural mechanisms to develop healthier skin cells. Composed of chains of nucleotides—the building blocks of DNA—these treatments are injected into the skin through multiple small injections. Polynucleotides help repair and rejuvenate skin cells, enhancing their natural functions in various ways.

For instance, polynucleotides stimulate the production of elastin and collagen, the essential proteins that keep skin firm and structured. They also offer anti-inflammatory benefits and improve the extracellular matrix of the skin. These properties help enhance:

  • Skin elasticity
  • Hydration
  • Inflammation reduction
  • Pigmentation balance
  • Skin tone and texture

By promoting overall skin health from within, polynucleotides provide a comprehensive approach to skin rejuvenation.

Why Polynucleotides Are a Game-Changer for Under-Eye Treatment

Traditional treatments for under-eye dark circles, such as dermal fillers, often focus on filling lost volume or targeting specific wrinkles. However, this approach isn’t always effective. Not everyone with dark circles has lost volume, so fillers might not address the root of the problem. Moreover, fillers offer only a temporary cosmetic fix without fundamentally improving the skin’s structure and health.

Polynucleotides, on the other hand, take a more holistic approach. They regenerate tissues, stimulate natural healing, and improve skin cell functioning, offering a more natural, long-term solution to under-eye rejuvenation. When applied under the eyes, polynucleotides work to enhance hydration, improve elasticity, and even out skin tone, resulting in visibly younger, healthier-looking skin.

Frequently Asked Questions

What Are the Side Effects of Polynucleotides Under the Eyes?

Side effects are usually minimal. Some people may experience mild bruising, bumps, or swelling, but these are temporary and typically resolve quickly.

How Long Do Polynucleotide Treatments Last?

Results from polynucleotide treatments continue to improve as skin cells regenerate. Visible improvements are usually seen around three months after the initial treatment, with benefits continuing for up to six months. Most people require just one maintenance session every 3-4 months to sustain the results.

How Long Does Each Treatment Take?

A polynucleotide treatment session under the eyes takes approximately 30 minutes, making it easy to fit into a busy schedule.

Polynucleotides: The Under-Eye Revolution

The introduction of polynucleotides in cosmetic dermatology marks a significant advancement in how we approach skin rejuvenation, especially for the challenging under-eye area. If you’re interested in exploring the benefits of polynucleotides, our expert team at Health & Aesthetics is here to help. We’ll work with you to create a tailored treatment plan that addresses your specific needs and goals, integrating the innovative power of polynucleotides into your skincare routine.

Book a consultation today to discover how polynucleotides can transform your under-eye area and restore your youthful appearance.

Client Reviews

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Chloe Ouwe profile picture
Chloe Ouwe
27 September 2025
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I recently had the pleasure of visiting this clinic for the very first time, and I cannot express how impressed and grateful I am for the entire experience. My first treatment was a hydrofacial with Alice, and from the moment I walked in, I was warmly welcomed by Elisha. She was so kind and made me feel comfortable right away, which instantly set the tone for a wonderful visit. The clinic itself is stunning—beautifully designed, clean, and with such a relaxing atmosphere that it truly feels like a luxury retreat. Alice, who carried out my hydrofacial, is an incredibly experienced therapist and also one of the kindest people I’ve ever met in a treatment setting. She explained everything clearly, was so gentle and professional throughout, and really took the time to make sure I was comfortable. The treatment left my skin absolutely glowing, and I could immediately see and feel the difference. Three weeks later, I returned for fractional and BBL laser treatments, and once again, I was welcomed with the same warmth and professionalism, this time by Amanda. She is incredibly sweet, polite, and attentive, and she made me feel completely at home throughout the process. These were treatments I had been considering for a long time, and I had spent quite a while searching for the right clinic where I would feel confident and cared for. I am so glad I found this place—it exceeded all of my expectations. The results have been fantastic, and I am truly thrilled with the improvement in my skin. Beyond the treatments themselves, what makes this clinic stand out is the team. Alice’s expertise and kindness, combined with Elisha and Amanda’s warm and welcoming nature, made me feel so valued and looked after. Everyone I’ve interacted with has been genuinely professional and caring, which makes such a difference when you are trusting someone with your skin and well-being. I am so happy and thankful to have discovered this clinic, and I will absolutely continue to come back. For anyone who has been searching for highly experienced therapists, excellent results, and a luxurious experience from start to finish, I cannot recommend this clinic enough. Thank you 💫🫶🏼✨🥰
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jackie Aston
25 September 2025
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I recently had treatment at NassifMD Clinic, and I couldn’t be happier with the care I received. From the moment I arrived, Elisha was warm, professional, and attentive, making me feel completely at ease. The clinic is modern, and clean. Which gave me great confidence in the standard of care. My treatment was explained clearly and carried out with a high level of professionalism. Amanda and Natalie made me feel at ease throughout. I really appreciated the friendly atmosphere and the way they made me feel. Overall, my experience was excellent. I would highly recommend NssifMD Clinic to anyone looking for quality medical care delivered with kindness and professionalism
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Sue Hadfield
23 September 2025
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After receiving my initial consultation, I knew I was in safe hands. Their knowledge and understanding of the various treatments available is the most apparent from the outset. They are truly professional; the staff are most welcoming, kind and helpful. The clinic is beautiful without feeling intimidating; I understand it is identical to Dr Naasif’s LA clinic, right down to the same artwork. No pressurised selling techniques, just a feeling of reassurance. - Sue
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Toni Tester
19 September 2025
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WOW what an amazing experience. From the moment I walked in, I was greeted by Elisha who is so warm and friendly. I was put at ease straight away. Amanda was amazing. Talked me through everything and no question was too much trouble to answer (and there were a lot). She even suggested removing a mole that was close to my eye. Natalie who did the treatment was awesome too. Kept asking if I was ok and informing me every step of the way what was happening and what she was going to do. I had the BBL X HALO which after numbing was more or less pain free. Best medical spa I have been to
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Pippa Robson
5 September 2025
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Gorgeous aesthetics and such lovely people. I had the scalp cleaning treatment, it was super relaxing and has made such a difference to my hair volume! Would 100% recommend!
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Samera Khan profile picture
Samera Khan
14 August 2025
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I had an incredible experience at Nassif MedSpa! Amanda and Dr Ryan, are very helpful and professional. From the moment I walked in, the staff was welcoming, professional, and attentive. They took the time to thoroughly explain the procedures and made me feel comfortable throughout the entire process. The results exceeded my expectations—I feel more confident and rejuvenated! The facility is immaculate and has such a calming atmosphere. Thank you, Nassif MedSpa, for your outstanding care and expertise. I highly recommend them to anyone looking for top-notch aesthetic treatments!
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Emanuele Simone Pagani
10 July 2025
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Very rude receptionist . Didn’t like them, I will go somewhere else
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WatchTheHorison
4 July 2025
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⭐⭐⭐⭐⭐ I recently had a Pro Fractional Laser treatment and couldn’t be happier with the entire experience. From start to finish, Amanda and Felicity were absolutely fantastic — professional, knowledgeable, and incredibly reassuring throughout the procedure. They explained everything clearly and made me feel completely at ease. The treatment itself was carried out with such care and precision. What really stood out to me was the aftercare – it was thorough, supportive, and made the recovery smooth and stress-free. Highly recommend Amanda and Felicity if you’re considering Pro Fractional or any advanced skin treatments – you’re in safe, expert hands!
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Yoana Kirilova
28 June 2025
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I had a full body laser hair removal session with Alice and couldn’t be happier. She listened carefully to my concerns and was incredibly thorough, gentle, and attentive throughout. The treatment was quick and significantly less painful than my previous experiences elsewhere. Alice made sure I was comfortable the entire time and was absolutely lovely—highly recommend!
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Sakina K profile picture
Sakina K
4 June 2025
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A lovely experience from the moment I arrived till leaving. Felicity was very friendly and welcoming. Alice was wonderful and the treatment was very relaxing! The consultation and treatment from Dr Jamie was very professional and thorough. Amazing overall and looking forward to my upcoming sessions 😊